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人FBLN5(NM_006329)ORF克隆
人FBLN5(NM_006329)ORF克隆
  • 商品货号:FO128907
  • 已售 5 件 | 评价 0 人次 | 关注度 375
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    • accession:NM_006329
    • 基因别名:FBLN5
    • 基因描述:Homo sapiens fibulin 5 (FBLN5), mRNA.
    • 载体: 现货载体
    • CDS区长度:1347
    • 翻译后氨基酸长度:448
    • 基因简介:The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列