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人BCL2L10(NM_020396)ORF克隆
人BCL2L10(NM_020396)ORF克隆
  • 商品货号:FO128155
  • 已售 5 件 | 评价 0 人次 | 关注度 382
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    • accession:NM_020396
    • 基因别名:BCL2L10
    • 基因描述:Homo sapiens BCL2-like 10 (apoptosis facilitator) (BCL2L10), mRNA.
    • 载体: 现货载体
    • CDS区长度:615
    • 翻译后氨基酸长度:204
    • 基因简介:The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列