• accession：NM_001048166
• 基因别名：STIL
• 基因描述：Homo sapiens SCL/TAL1 interrupting locus (STIL), transcript variant 1, mRNA.
• 载体： 现货载体
• CDS区长度：3867
• 翻译后氨基酸长度：1288
• TranscriptVariant：This variant (1) encodes the longest isoform (1).
• 基因简介：This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGAGCCTATATATCCTTTTGCACGGCCCCAGATGAATACCAGGTTTCCTTCAAGCAGGATGGTACCTTTCCACTTTCCTCCATCAAAATGTGCACTTTGGAACCCAACGCCAACTGGAGATTTCATCTACTTACATCTCAGTTACTACAGAAATCCAAAGCTTGTGGTGACTGAGAAGACCATCCGACTTGCTTATCGTCATGCTAAGCAGAATAAAAAAAATTCGTCATGCTTTTTACTTGGTTCTCTGACAGCAGACGAAGATGAAGAAGGTGTAACATTGACAGTAGATCGCTTTGATCCTGGTCGAGAAGTACCTGAATGCCTAGAAATAACCCCTACTGCTTCTCTTCCTGGGGACTTTTTGATTCCATGCAAAGTTCATACTCAAGAACTTTGTTCAAGAGAAATGATAGTTCACAGTGTAGATGACTTCAGTTCAGCTTTAAAGGCTCTACAGTGCCATATATGTAGCAAAGATTCCTTGGACTGTGGTAAGCTGCTTTCCCTAAGAGTTCATATCACTTCCAGGGAGAGTTTGGACAGTGTGGAATTTGACTTGCATTGGGCAGCAGTAACTCTAGCAAATAACTTTAAATGCACACCTGTGAAGCCCATCCCCATTATTCCAACAGCTCTGGCAAGAAACTTGAGCAGTAATCTGAATATTTCTCAAGTTCAAGGGACTTATAAATATGGATATCTTACCATGGATGAAACACGCAAATTGTTACTTTTGTTGGAATCTGATCCCAAGGTTTATTCTCTACCATTGGTGGGAATTTGGCTGTCTGGAATTACACATATCTATAGTCCTCAGGTATGGGCTTGCTGTTTGCGATACATATTCAATTCTTCTGTTCAAGAAAGGGTTTTTTCAGAATCTGGAAATTTCATCATAGTTCTCTATTCTATGACACATAAGGAACCTGAGTTTTATGAATGCTTCCCTTGTGATGGCAAGATACCTGACTTTCGGTTTCAGTTGCTAACCAGTAAGGAAACATTACATCTTTTCAAAAATGTTGAACCTCCTGACAAAAATCCAATCCGTTGTGAACTGAGCGCTGAAAGCCAAAATGCAGAAACAGAGTTTTTCAGTAAGGCTTCCAAGAATTTTTCAATTAAGAGGTCTTCCCAAAAGTTATCTTCTGGGAAGATGCCAATACATGATCACGACTCTGGTGTTGAAGATGAAGATTTTTCTCCAAGACCAATTCCTAGTCCTCATCCAGTGAGTCAGAAGATTTCTAAGATCCAACCATCAGTTCCTGAACTTTCACTTGTGTTGGATGGCAATTTCATAGAATCAAACCCTCTGCCTACTCCATTGGAAATGGTGAATAATGAAAATCCTCCTTTGATTAACCACTTGGAACACTTGAAGCCATTGCAACCCCAGCTTTATGATGAGAAACACAGTCCAGAAGTTGAAGCTGGAGAGCCTTCCTTGAGAGGAATACCAAATCAGTTAAACCAGGATAAACCAGCTCTTTTGAGACACTGCAAAGTAAGACAGCCACCTGCCTATAAGAAAGGGAACCCCCATACCAGGAACAGTATTAAACCATCTTCTCATAATGGGCCATCTCATGATATATTTGAAAAGCTCCAAACAGTTTCTGCTGGAAATGTACAAAACGAAGAGTATCCTATAAGACCCTCCACACTTAATTCTAGGCAGTCTTCTCTTGCCCCGCAGTCCCAACCACACGATTTTGTTTTTTCACCCCATAATTCAGGAAGACCAATGGAACTTCAGATACCTACTCCCCCACTGCCATCTTACTGTTCCACAAACGTTTGCAGGTGTTGTCAGCATCATAGTCATATTCAATATAGTCCGCTAAATTCTTGGCAAGGAGCAAACACAGTTGGATCCATTCAAGATGTCCAGTCTGAAGCCCTTCAAAAGCATTCATTATTTCACCCAAGTGGATGTCCAGCCCTGTACTGTAATGCATTCTGTTCTTCAAGTAGTCCTATAGCCTTGAGACCTCAGGGAGATATGGGCAGTTGTTCTCCCCACAGCAATATTGAACCATCGCCTGTGGCAAGACCGCCTTCACATATGGACTTATGTAACCCACAGCCTTGCACAGTGTGCATGCACACACCCAAGACTGAGTCAGATAATGGAATGATGGGACTATCTCCAGATGCATATCGGTTCCTCACAGAACAAGACAGACAGCTAAGACTACTTCAGGCACAGATTCAGCGTTTGTTGGAAGCACAGTCTCTGATGCCCTGTTCCCCTAAGACAACTGCTGTTGAAGACACAGTGCAAGCTGGAAGACAAATGGAGTTGGTTTCTGTGGAAGCACAGTCTTCCCCTGGCTTGCACATGAGAAAAGGTGTAAGCATTGCTGTGAGCACAGGTGCTAGCTTGTTTTGGAATGCAGCAGGTGAGGATCAAGAGCCTGACTCTCAAATGAAGCAAGATGATACCAAAATTTCCAGTGAGGACATGAATTTTTCTGTCGATATTAATAATGAAGTCACAAGTCTTCCAGGTAGTGCATCTTCATTAAAAGCAGTTGATATTCCCAGTTTTGAAGAGAGCAACATTGCTGTGGAAGAAGAATTTAACCAGCCACTTTCTGTATCCAACAGCTCTTCTCTAGTTGTGAGAAAAGAACCTGATGTACCTGTGTTCTTTCCAAGTGGCCAGCTGGCAGAAAGTGTAAGCATGTGTTTACAGACTGGACCAACAGGGGGTGCCAGTAACAATTCTGAAACATCAGAGGAACCAAAAATTGAGCATGTAATGCAACCCTTGCTTCATCAACCATCAGATAACCAGAAAATTTACCAGGATTTATTGGGTCAAGTAAACCACCTATTAAATAGTTCCTCCAAGGAAACTGAGCAGCCGTCTACCAAAGCAGTAATTATCAGTCATGAATGCACCAGAACCCAAAACGTTTACCATACAAAGAAAAAAACACATCATTCAAGACTGGTGGACAAAGATTGTGTCCTTAATGCAACTCTTAAGCAACTAAGAAGCCTTGGAGTAAAAATTGATTCTCCCACTAAAGTGAAGAAAAATGCACATAACGTGGATCACGCCAGTGTGTTGGCATGCATCAGCCCAGAAGCAGTGATCTCTGGATTAAACTGCATGTCATTTGCTAATGTTGGCATGAGCGGCTTAAGCCCCAATGGTGTGGATTTGAGCATGGAGGCAAATGCTATAGCTCTGAAATATTTAAATGAAAATCAGCTGTCACAACTGTCTGTCACTCGATCGAACCAAAATAATTGTGACCCATTCAGCCTTCTCCATATTAATACAGACAGAAGCACAGTGGGGCTTAGTTTAATTTCACCAAACAACATGTCATTTGCAACCAAAAAATATATGAAGAGATATGGACTCCTACAAAGCAGTGACAATAGTGAAGATGAAGAGGAACCTCCCGACAATGCAGATAGCAAGAGTGAATATTTATTGAATCAGAACCTTAGGTCCATACCTGAACAGCTTGGTGGTCAGAAAGAGCCTTCTAAGAATGACCATGAAATAATTAATTGTTCTAACTGTGAATCTGTGGGGACCAACGCAGATACGCCAGTATTGAGAAATATTACAAATGAAGTTTTGCAGACAAAAGCAAAACAGCAGTTGACTGAAAAGCCAGCTTTCTTAGTAAAGAACCTTAAACCAAGTCCTGCAGTGAACCTTCGAACCGGGAAAGCAGAGTTCACTCAACATCCTGAGAAAGAAAATGAAGGGGACATTACAATTTTTCCTGAAAGTTTGCAACCTTCTGAAACGCTAAAGCAGATGAATAGCATGAATTCAGTAGGCACCTTCTTAGATGTAAAACGTCTCAGACAGTTACCAAAATTATTTTAA

翻译后氨基酸参数序列： 点击查看序列

ATGGAGCCTATATATCCTTTTGCACGGCCCCAGATGAATACCAGGTTTCCTTCAAGCAGGATGGTACCTTTCCACTTTCCTCCATCAAAATGTGCACTTTGGAACCCAACGCCAACTGGAGATTTCATCTACTTACATCTCAGTTACTACAGAAATCCAAAGCTTGTGGTGACTGAGAAGACCATCCGACTTGCTTATCGTCATGCTAAGCAGAATAAAAAAAATTCGTCATGCTTTTTACTTGGTTCTCTGACAGCAGACGAAGATGAAGAAGGTGTAACATTGACAGTAGATCGCTTTGATCCTGGTCGAGAAGTACCTGAATGCCTAGAAATAACCCCTACTGCTTCTCTTCCTGGGGACTTTTTGATTCCATGCAAAGTTCATACTCAAGAACTTTGTTCAAGAGAAATGATAGTTCACAGTGTAGATGACTTCAGTTCAGCTTTAAAGGCTCTACAGTGCCATATATGTAGCAAAGATTCCTTGGACTGTGGTAAGCTGCTTTCCCTAAGAGTTCATATCACTTCCAGGGAGAGTTTGGACAGTGTGGAATTTGACTTGCATTGGGCAGCAGTAACTCTAGCAAATAACTTTAAATGCACACCTGTGAAGCCCATCCCCATTATTCCAACAGCTCTGGCAAGAAACTTGAGCAGTAATCTGAATATTTCTCAAGTTCAAGGGACTTATAAATATGGATATCTTACCATGGATGAAACACGCAAATTGTTACTTTTGTTGGAATCTGATCCCAAGGTTTATTCTCTACCATTGGTGGGAATTTGGCTGTCTGGAATTACACATATCTATAGTCCTCAGGTATGGGCTTGCTGTTTGCGATACATATTCAATTCTTCTGTTCAAGAAAGGGTTTTTTCAGAATCTGGAAATTTCATCATAGTTCTCTATTCTATGACACATAAGGAACCTGAGTTTTATGAATGCTTCCCTTGTGATGGCAAGATACCTGACTTTCGGTTTCAGTTGCTAACCAGTAAGGAAACATTACATCTTTTCAAAAATGTTGAACCTCCTGACAAAAATCCAATCCGTTGTGAACTGAGCGCTGAAAGCCAAAATGCAGAAACAGAGTTTTTCAGTAAGGCTTCCAAGAATTTTTCAATTAAGAGGTCTTCCCAAAAGTTATCTTCTGGGAAGATGCCAATACATGATCACGACTCTGGTGTTGAAGATGAAGATTTTTCTCCAAGACCAATTCCTAGTCCTCATCCAGTGAGTCAGAAGATTTCTAAGATCCAACCATCAGTTCCTGAACTTTCACTTGTGTTGGATGGCAATTTCATAGAATCAAACCCTCTGCCTACTCCATTGGAAATGGTGAATAATGAAAATCCTCCTTTGATTAACCACTTGGAACACTTGAAGCCATTGCAACCCCAGCTTTATGATGAGAAACACAGTCCAGAAGTTGAAGCTGGAGAGCCTTCCTTGAGAGGAATACCAAATCAGTTAAACCAGGATAAACCAGCTCTTTTGAGACACTGCAAAGTAAGACAGCCACCTGCCTATAAGAAAGGGAACCCCCATACCAGGAACAGTATTAAACCATCTTCTCATAATGGGCCATCTCATGATATATTTGAAAAGCTCCAAACAGTTTCTGCTGGAAATGTACAAAACGAAGAGTATCCTATAAGACCCTCCACACTTAATTCTAGGCAGTCTTCTCTTGCCCCGCAGTCCCAACCACACGATTTTGTTTTTTCACCCCATAATTCAGGAAGACCAATGGAACTTCAGATACCTACTCCCCCACTGCCATCTTACTGTTCCACAAACGTTTGCAGGTGTTGTCAGCATCATAGTCATATTCAATATAGTCCGCTAAATTCTTGGCAAGGAGCAAACACAGTTGGATCCATTCAAGATGTCCAGTCTGAAGCCCTTCAAAAGCATTCATTATTTCACCCAAGTGGATGTCCAGCCCTGTACTGTAATGCATTCTGTTCTTCAAGTAGTCCTATAGCCTTGAGACCTCAGGGAGATATGGGCAGTTGTTCTCCCCACAGCAATATTGAACCATCGCCTGTGGCAAGACCGCCTTCACATATGGACTTATGTAACCCACAGCCTTGCACAGTGTGCATGCACACACCCAAGACTGAGTCAGATAATGGAATGATGGGACTATCTCCAGATGCATATCGGTTCCTCACAGAACAAGACAGACAGCTAAGACTACTTCAGGCACAGATTCAGCGTTTGTTGGAAGCACAGTCTCTGATGCCCTGTTCCCCTAAGACAACTGCTGTTGAAGACACAGTGCAAGCTGGAAGACAAATGGAGTTGGTTTCTGTGGAAGCACAGTCTTCCCCTGGCTTGCACATGAGAAAAGGTGTAAGCATTGCTGTGAGCACAGGTGCTAGCTTGTTTTGGAATGCAGCAGGTGAGGATCAAGAGCCTGACTCTCAAATGAAGCAAGATGATACCAAAATTTCCAGTGAGGACATGAATTTTTCTGTCGATATTAATAATGAAGTCACAAGTCTTCCAGGTAGTGCATCTTCATTAAAAGCAGTTGATATTCCCAGTTTTGAAGAGAGCAACATTGCTGTGGAAGAAGAATTTAACCAGCCACTTTCTGTATCCAACAGCTCTTCTCTAGTTGTGAGAAAAGAACCTGATGTACCTGTGTTCTTTCCAAGTGGCCAGCTGGCAGAAAGTGTAAGCATGTGTTTACAGACTGGACCAACAGGGGGTGCCAGTAACAATTCTGAAACATCAGAGGAACCAAAAATTGAGCATGTAATGCAACCCTTGCTTCATCAACCATCAGATAACCAGAAAATTTACCAGGATTTATTGGGTCAAGTAAACCACCTATTAAATAGTTCCTCCAAGGAAACTGAGCAGCCGTCTACCAAAGCAGTAATTATCAGTCATGAATGCACCAGAACCCAAAACGTTTACCATACAAAGAAAAAAACACATCATTCAAGACTGGTGGACAAAGATTGTGTCCTTAATGCAACTCTTAAGCAACTAAGAAGCCTTGGAGTAAAAATTGATTCTCCCACTAAAGTGAAGAAAAATGCACATAACGTGGATCACGCCAGTGTGTTGGCATGCATCAGCCCAGAAGCAGTGATCTCTGGATTAAACTGCATGTCATTTGCTAATGTTGGCATGAGCGGCTTAAGCCCCAATGGTGTGGATTTGAGCATGGAGGCAAATGCTATAGCTCTGAAATATTTAAATGAAAATCAGCTGTCACAACTGTCTGTCACTCGATCGAACCAAAATAATTGTGACCCATTCAGCCTTCTCCATATTAATACAGACAGAAGCACAGTGGGGCTTAGTTTAATTTCACCAAACAACATGTCATTTGCAACCAAAAAATATATGAAGAGATATGGACTCCTACAAAGCAGTGACAATAGTGAAGATGAAGAGGAACCTCCCGACAATGCAGATAGCAAGAGTGAATATTTATTGAATCAGAACCTTAGGTCCATACCTGAACAGCTTGGTGGTCAGAAAGAGCCTTCTAAGAATGACCATGAAATAATTAATTGTTCTAACTGTGAATCTGTGGGGACCAACGCAGATACGCCAGTATTGAGAAATATTACAAATGAAGTTTTGCAGACAAAAGCAAAACAGCAGTTGACTGAAAAGCCAGCTTTCTTAGTAAAGAACCTTAAACCAAGTCCTGCAGTGAACCTTCGAACCGGGAAAGCAGAGTTCACTCAACATCCTGAGAAAGAAAATGAAGGGGACATTACAATTTTTCCTGAAAGTTTGCAACCTTCTGAAACGCTAAAGCAGATGAATAGCATGAATTCAGTAGGCACCTTCTTAGATGTAAAACGTCTCAGACAGTTACCAAAATTATTTTAA