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人CSE1L(NM_001316)ORF克隆
人CSE1L(NM_001316)ORF克隆
  • 商品货号:FO126529
  • 已售 5 件 | 评价 0 人次 | 关注度 417
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    • accession:NM_001316
    • 基因别名:CSE1L
    • 基因描述:Homo sapiens CSE1 chromosome segregation 1-like (yeast) (CSE1L), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:2916
    • 翻译后氨基酸长度:971
    • TranscriptVariant:This variant (1) represents the predominant transcript, and encodes the longer isoform (1).
    • 基因简介:Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列