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人F11(NM_000128)ORF克隆
人F11(NM_000128)ORF克隆
  • 商品货号:FO126300
  • 已售 5 件 | 评价 0 人次 | 关注度 362
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    • accession:NM_000128
    • 基因别名:F11
    • 基因描述:Homo sapiens coagulation factor XI (F11), mRNA.
    • 载体: 现货载体
    • CDS区长度:1878
    • 翻译后氨基酸长度:625
    • 基因简介:This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列