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人 EP300 (NM_001429) cDNA克隆
人 EP300 (NM_001429) cDNA克隆
  • 商品货号:FC172801
  • 已售 3 件 | 评价 0 人次 | 关注度 509
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    • accession:NM_001429
    • 基因别名:EP300
    • 基因描述:Homo sapiens E1A binding protein p300 (EP300), mRNA.
    • 载体:现货载体
    • CDS区长度:7245
    • 翻译后氨基酸长度:2414
    • 基因简介:This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列