- accession:NM_001005474
- 基因别名:NFKBIZ
- 基因描述:Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (NFKBIZ), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1857
- 翻译后氨基酸长度:618
- TranscriptVariant:This variant (2) contains alternative 5' non-coding exons compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in a shorter isoform (b) compared to isoform a.
- 基因简介:This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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