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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 NSD1 (NM_172349) cDNA克隆
人 NSD1 (NM_172349) cDNA克隆
人 NSD1 (NM_172349) cDNA克隆
  • 商品货号：FC159891
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    • accession：NM_172349
    • 基因别名：NSD1
    • 基因描述：Homo sapiens nuclear receptor binding SET domain protein 1 (NSD1), transcript variant 1, mRNA.
    • 载体：现货载体
    • CDS区长度：7284
    • 翻译后氨基酸长度：2427
    • TranscriptVariant：This variant (1), also known as ARA267-alpha, differs in the 5' UTR and coding region, compared to variant 2. It encodes a shorter isoform (a), that has a distinct N-terminus compared to isoform b.
    • 基因简介：This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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