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- accession：NM_022892
- 基因别名：NAIP
- 基因描述：Homo sapiens NLR family, apoptosis inhibitory protein (NAIP), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：3726
- 翻译后氨基酸长度：1241
- TranscriptVariant：This variant (2), also known as psiNAIP, lacks two internal exons in the 5' coding region, as compared to variant 1. The resulting isoform (2) has an alternate and shorter N-terminus, as compared to isoform 1.
- 基因简介：This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
