×
![]()
- accession：NM_001113202
- 基因别名：NACA
- 基因描述：Homo sapiens nascent polypeptide-associated complex alpha subunit (NACA), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：648
- 翻译后氨基酸长度：215
- TranscriptVariant：This variant (4) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform b, which is shorter than isoform a.
- 基因简介：The protein encoded by this gene associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). NAC binds to nascent proteins as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. However, nascent proteins with an exposed signal peptide will not be bound by the encoded protein, enabling them to bind the SRP and enter the secretory pathway. This protein has been determined to be an IgE autoantigen in atopic dermatitis patients. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
