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人 MYO9B (NM_001130065) cDNA克隆
人 MYO9B (NM_001130065) cDNA克隆
  • 商品货号:FC154888
  • 已售 5 件 | 评价 0 人次 | 关注度 340
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    • accession:NM_001130065
    • 基因别名:MYO9B
    • 基因描述:Homo sapiens myosin IXB (MYO9B), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:6069
    • 翻译后氨基酸长度:2022
    • TranscriptVariant:This variant (2) differs in the 3' UTR and 3' coding region due to the use of an alternate splice site in the penultimate exon. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    • 基因简介:This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列