- accession:NM_002467
- 基因别名:MYC
- 基因描述:Homo sapiens v-myc avian myelocytomatosis viral oncogene homolog (MYC), mRNA.
- 载体:现货载体
- CDS区长度:1365
- 翻译后氨基酸长度:454
- 基因简介:The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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