- accession:NM_001227
- 基因别名:CASP7
- 基因描述:Homo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant a, mRNA.
- 载体: 现货载体
- CDS区长度:912
- 翻译后氨基酸长度:303
- TranscriptVariant:This variant (a, also known as alpha) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant d. Variants a, c and e encode the same isoform (alpha), which has a shorter N-terminus compared to isoform delta.
- 基因简介:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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