×
欢迎光临本店! 登录 注册

人KRT8(NM_002273)ORF克隆
人KRT8(NM_002273)ORF克隆
  • 商品货号:FO110980
  • 已售 3 件 | 评价 0 人次 | 关注度 499
    浏览历史清除
    • accession:NM_002273
    • 基因别名:KRT8
    • 基因描述:Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.
    • 载体: 现货载体
    • CDS区长度:1452
    • 翻译后氨基酸长度:483
    • TranscriptVariant:This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation in a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform 2.
    • 基因简介:This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列