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人 HBA1 (NM_000558) cDNA克隆
人 HBA1 (NM_000558) cDNA克隆
  • 商品货号:FC116611
  • 已售 4 件 | 评价 0 人次 | 关注度 379
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    • accession:NM_000558
    • 基因别名:HBA1
    • 基因描述:Homo sapiens hemoglobin, alpha 1 (HBA1), mRNA.
    • 载体:现货载体
    • CDS区长度:429
    • 翻译后氨基酸长度:142
    • 基因简介:The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列