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- accession：NM_001166691
- 基因别名：TTK
- 基因描述：Homo sapiens TTK protein kinase (TTK), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：2571
- 翻译后氨基酸长度：856
- TranscriptVariant：This variant (2) uses alternate in-frame splice sites in the 5' UTR and in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
- 基因简介：This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
