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- accession：NM_198830
- 基因别名：ACLY
- 基因描述：Homo sapiens ATP citrate lyase (ACLY), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：3276
- 翻译后氨基酸长度：1091
- TranscriptVariant：This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. This results in a shorter isoform (2), compared to isoform 1.
- 基因简介：ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
