- accession:NM_001261464
- 基因别名:ADAM15
- 基因描述:Homo sapiens ADAM metallopeptidase domain 15 (ADAM15), transcript variant 7, mRNA.
- 载体:现货载体
- CDS区长度:2475
- 翻译后氨基酸长度:824
- TranscriptVariant:This variant (7) lacks two alternate in-frame exons in the 3' coding region compared to variant 6. The resulting protein (isoform 7) is shorter compared to isoform 6.
- 基因简介:The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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