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- accession：NM_207196
- 基因别名：ADAM15
- 基因描述：Homo sapiens ADAM metallopeptidase domain 15 (ADAM15), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：2589
- 翻译后氨基酸长度：862
- TranscriptVariant：This variant (5) uses an alternative splice site within the coding region compared to variant 6. The translation frame remains the same. The resulting isoform (5) lacks an amino acid, as compared to the longest isoform (6).
- 基因简介：The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
