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- accession：NM_207191
- 基因别名：ADAM15
- 基因描述：Homo sapiens ADAM metallopeptidase domain 15 (ADAM15), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：2319
- 翻译后氨基酸长度：772
- TranscriptVariant：This variant (1) lacks three exons in the coding region compared to variant 6, one of which causes a translation frameshift. The resulting isoform (1) has a distinct and shorter C-terminus, as compared to the longest isoform (6).
- 基因简介：The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
