- accession:NM_013254
- 基因别名:TBK1
- 基因描述:Homo sapiens TANK-binding kinase 1 (TBK1), mRNA.
- 载体:pcDNA3.1-3xFlag-C
- CDS区长度:2190
- 翻译后氨基酸长度:729
- 基因简介:The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列