- accession:NM_001282338
- 基因别名:PLS3
- 基因描述:Homo sapiens plastin 3 (PLS3), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:1758
- 翻译后氨基酸长度:585
- TranscriptVariant:This variant (5) contains an alternate 5' non-coding exon and a novel exon in the 5' region that results in translation initiation from an in-frame downstream start codon compared to variant 1. The encoded isoform (4) has a shorter N-terminus compared to isoform 1.
- 基因简介:Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
- 规格:10ul 质粒
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