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- accession：NM_005356
- 基因别名：LCK
- 基因描述：Homo sapiens lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1530
- 翻译后氨基酸长度：509
- TranscriptVariant：This variant (2) is transcribed from the distal type II promoter and contains a distinct 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
- 基因简介：This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
