- accession:NM_014911
- 基因别名:AAK1
- 基因描述:Homo sapiens AP2 associated kinase 1 (AAK1), mRNA.
- 载体:现货载体
- CDS区长度:2886
- 翻译后氨基酸长度:961
- 基因简介:Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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