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- accession：NM_001042465
- 基因别名：PSAP
- 基因描述：Homo sapiens prosaposin (PSAP), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1584
- 翻译后氨基酸长度：527
- TranscriptVariant：This variant (2) represents the longest transcript and encodes the longest isoform (b).
- 基因简介：This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
