- accession:NM_001017520
- 基因别名:DNTT
- 基因描述:Homo sapiens DNA nucleotidylexotransferase (DNTT), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1527
- 翻译后氨基酸长度:508
- TranscriptVariant:This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes an isoform (2), which is shorter than isoform 1.
- 基因简介:This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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