• accession：NM_001256712
• 基因别名：ANAPC10
• 基因描述：Homo sapiens anaphase promoting complex subunit 10 (ANAPC10), transcript variant 8, mRNA.
• 载体：现货载体
• CDS区长度：252
• 翻译后氨基酸长度：83
• TranscriptVariant：This variant (8) uses an alternate splice site in the 5' UTR and lacks an exon in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.
• 基因简介：ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGACTACACCAAACAAGACACCTCCTGGTGCTGACCCCAAGCAGTTGGAAAGGACTGGAACAGTACGGG
AAATTGGGTCACAAGCTGTTTGGTCACTCTCATCTTGCAAACCAGGATTTGGAGTGGATCAGTTACGAGA
TGACAATCTAGAAACTTATTGGCAATCAGATGGTTCCCAGCCTCATTTAGTGAACATCCAATTCAGCAAC
TTGAGTTGGTGGAACCAAGTGGCTGGATTCATGTTCCCTTAA

翻译后氨基酸参数序列： 点击查看序列

ATGACTACACCAAACAAGACACCTCCTGGTGCTGACCCCAAGCAGTTGGAAAGGACTGGAACAGTACGGG
AAATTGGGTCACAAGCTGTTTGGTCACTCTCATCTTGCAAACCAGGATTTGGAGTGGATCAGTTACGAGA
TGACAATCTAGAAACTTATTGGCAATCAGATGGTTCCCAGCCTCATTTAGTGAACATCCAATTCAGCAAC
TTGAGTTGGTGGAACCAAGTGGCTGGATTCATGTTCCCTTAA