×
![]()
- accession：NM_005590
- 基因别名：MRE11A
- 基因描述：Homo sapiens MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：2043
- 翻译后氨基酸长度：680
- TranscriptVariant：This variant (2) differs in the 5' UTR and lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform 2 lacks an internal segment, compared to isoform 1.
- 基因简介：This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
