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人 EGLN1 (NM_022051) cDNA克隆
人 EGLN1 (NM_022051) cDNA克隆
  • 商品货号:FC109576
  • ¥1100元
    已售 6 件 | 评价 0 人次 | 关注度 354
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    • accession:NM_022051
    • 基因别名:EGLN1
    • 基因描述:Homo sapiens egl-9 family hypoxia-inducible factor 1 (EGLN1), mRNA.
    • 载体:现货载体
    • CDS区长度:1281
    • 翻译后氨基酸长度:426
    • 基因简介:The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列