- accession:NM_016066
- 基因别名:GLRX2
- 基因描述:Homo sapiens glutaredoxin 2 (GLRX2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:498
- 翻译后氨基酸长度:165
- TranscriptVariant:This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as Grx2b).
- 基因简介:The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
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