- accession:NM_199413
- 基因别名:PRC1
- 基因描述:Homo sapiens protein regulator of cytokinesis 1 (PRC1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1821
- 翻译后氨基酸长度:606
- TranscriptVariant:This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
- 基因简介:This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
- 规格:10ul 质粒
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