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人PTPRN2(NM_130843)ORF克隆
人PTPRN2(NM_130843)ORF克隆
  • 商品货号:FO158752
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    • accession:NM_130843
    • 基因别名:PTPRN2
    • 基因描述:Homo sapiens protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, mRNA.
    • 载体:现货载体
    • CDS区长度:2961
    • 翻译后氨基酸长度:986
    • TranscriptVariant:This variant (3) lacks an internal fragment within the coding region when compared to variant 1. The translation remains in-frame, and thus results in a protein that lacks a 29 aa internal segment, as compared to isoform (1).
    • 基因简介:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列