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人HR(NM_005144)ORF克隆
人HR(NM_005144)ORF克隆
  • 商品货号:FO157469
  • ¥2800元
    已售 4 件 | 评价 0 人次 | 关注度 643
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    • accession:NM_005144
    • 基因别名:HR
    • 基因描述:Homo sapiens hair growth associated (HR), transcript variant 1, mRNA.
    • 载体:现货载体
    • CDS区长度:3570
    • 翻译后氨基酸长度:1189
    • TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (a).
    • 基因简介:This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by multiple regulatory ORFs that exist upstream of the primary ORF. Mutations in one of these upstream ORFs, U2HR, cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列