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- accession：NM_018984
- 基因别名：SSH1
- 基因描述：Homo sapiens slingshot protein phosphatase 1 (SSH1), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：3150
- 翻译后氨基酸长度：1049
- TranscriptVariant：This variant (1) represents the longest transcript and encodes the longest isoform (1, also known as SSH-1L). This isoform has been shown to be enzymatically active (PMID:11832213).
- 基因简介：The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- 载体信息：自有图片地址
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
