• accession：NM_002504
• 基因别名：NFX1
• 基因描述：Homo sapiens nuclear transcription factor, X-box binding 1 (NFX1), transcript variant 1, mRNA.
• 载体：现货载体
• CDS区长度：3363
• 翻译后氨基酸长度：1120
• TranscriptVariant：This variant (1) is the longest transcript and encodes the longest isoform (1).
• 基因简介：MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGCGGAGGCGCCTCCTGTCTCAGGTACTTTTAAATTCAATACAGATGCTGCTGAATTCATTCCTCAGGAGAAAAAAAATTCTGGTCTAAATTGTGGGACTCAAAGGAGACTAGACTCTAATAGGATTGGTAGAAGAAATTACAGTTCACCACCTCCCTGTCACCTTTCCAGGCAGGTCCCTTATGATGAAATCTCTGCTGTTCATCAGCATAGTTATCATCCGTCAGGAAGCAAACCTAAGAGTCAGCAGACGTCTTTCCAGTCCTCTCCTTGTAATAAATCGCCCAAGAGCCATGGCCTTCAGAATCAACCTTGGCAGAAATTGAGGAATGAGAAGCACCATATCAGAGTCAAGAAAGCACAGAGTCTTGCTGAGCAGACCTCAGATACAGCTGGATTAGAGAGCTCGACCAGATCAGAGAGTGGGACAGACCTCAGAGAGCATAGTCCTTCTGAGAGTGAGAAGGAAGTTGTGGGTGCAGATCCCAGGGGAGCAAAACCCAAAAAAGCAACACAGTTTGTATACAGCTATGGTAGAGGACCAAAAGTCAAGGGGAAACTCAAATGTGAATGGAGTAACCGAACAACTCCAAAACCGGAGGATGCTGGACCCGAAAGTACCAAACCTGTGGGGGTTTTCCACCCTGACTCTTCAGAGGCATCCTCTAGAAAAGGAGTATTGGATGGGTATGGAGCCAGACGAAATGAGCAGAGAAGATACCCACAGAAAAGGCCTCCCTGGGAAGTGGAGGGGGCCAGGCCACGACCAGGCAGAAATCCACCAAAACAGGAGGGCCACCGACATACAAACGCAGGACACAGAAACAACATGGGCCCCATTCCAAAGGATGACCTCAATGAAAGACCAGCAAAATCTACCTGTGACAGTGAGAACTTGGCAGTCATCAACAAGTCTTCCAGGAGGGTTGACCAAGAGAAATGCACTGTACGGAGGCAGGATCCTCAAGTAGTATCTCCTTTCTCCCGAGGCAAACAGAACCATGTGCTAAAGAATGTGGAAACGCACACAGGTTCTCTAATTGAACAACTAACAACAGAAAAATACGAGTGCATGGTGTGCTGTGAATTGGTTCGTGTCACGGCCCCAGTGTGGAGTTGTCAGAGCTGTTACCATGTGTTTCATTTGAACTGCATAAAGAAATGGGCAAGGTCTCCAGCATCTCAAGCAGATGGCCAGAGTGGTTGGAGGTGCCCTGCCTGTCAGAATGTTTCTGCACATGTTCCTAATACCTACACTTGTTTCTGTGGCAAGGTAAAGAATCCTGAGTGGAGCAGAAATGAAATTCCACATAGCTGTGGTGAGGTTTGTAGAAAGAAACAGCCTGGCCAGGACTGCCCACATTCCTGTAACCTTCTCTGCCATCCAGGACCCTGCCCACCCTGCCCTGCCTTTATGACAAAAACATGTGAATGTGGACGAACCAGGCACACAGTTCGCTGTGGTCAGGCTGTCTCAGTCCACTGTTCTAACCCATGTGAGAATATTTTGAACTGTGGTCAGCACCAGTGTGCTGAGCTGTGCCATGGGGGTCAGTGCCAGCCTTGCCAGATCATTTTGAACCAGGTATGCTATTGCGGCAGCACCTCCCGAGATGTGTTATGTGGAACCGATGTAGGAAAGTCTGATGGATTTGGGGATTTCAGCTGTTTAAAGATATGTGGCAAGGACTTGAAATGCGGTAACCATACATGTTCGCAAGTGTGCCACCCTCAGCCCTGCCAGCAATGCCCACGGCTCCCCCAGCTGGTGCGCTGTTGCCCCTGTGGCCAAACTCCTCTCAGCCAATTGCTAGAACTTGGAAGTAGTAGTCGGAAAACATGCATGGACCCTGTGCCTTCATGTGGAAAAGTGTGCGGCAAGCCTCTGCCTTGTGGTTCCTTAGATTTCATTCATACCTGTGAAAAGCTCTGCCATGAAGGAGACTGTGGACCATGCTCTCGCACATCAGTTATTTCCTGCAGATGCTCTTTCAGAACAAAGGAGCTTCCATGTACCAGTCTCAAAAGTGAAGATGCTACATTTATGTGTGACAAGCGGTGTAACAAGAAACGGTTGTGTGGACGGCATAAATGTAATGAGATATGCTGTGTGGATAAGGAGCACAAGTGTCCTTTGATTTGTGGGAGGAAACTCCGTTGTGGCCTTCATAGGTGTGAAGAACCTTGTCATCGTGGAAACTGCCAGACATGCTGGCAAGCCAGTTTTGATGAATTAACCTGCCATTGTGGTGCATCAGTGATTTACCCTCCAGTTCCCTGTGGTACTAGGCCCCCTGAATGTACCCAAACCTGCGCTAGAGTCCATGAGTGTGACCATCCAGTATATCATTCTTGTCATAGTGAGGAGAAGTGTCCCCCTTGCACTTTCCTAACTCAGAAGTGGTGCATGGGCAAGCATGAGTTTCGGAGCAACATCCCCTGTCACCTGGTTGATATCTCTTGCGGATTACCCTGCAGTGCCACGCTACCATGTGGGATGCACAAATGTCAGAGACTCTGTCACAAAGGGGAGTGTCTTGTGGATGAGCCCTGCAAGCAGCCCTGCACCACCCCCAGAGCTGACTGTGGTCACCCGTGTATGGCACCCTGCCATACCAGCTCACCCTGCCCTGTGACTGCTTGTAAAGCTAAGGTAGAGCTACAGTGTGAATGTGGACGAAGAAAAGAGATGGTGATTTGCTCTGAAGCATCTAGTACTTATCAAAGAATAGCTGCAATCTCCATGGCCTCTAAGATAACAGACATGCAGCTTGGAGGTTCAGTGGAGATCAGCAAGTTAATTACCAAAAAGGAAGTTCATCAAGCCAGGCTGGAGTGTGATGAGGAGTGTTCAGCCTTGGAAAGGAAAAAGAGATTAGCAGAGGCATTTCATATCAGTGAGGATTCTGATCCTTTCAATATACGTTCTTCAGGGTCAAAATTCAGTGATAGTTTGAAAGAAGATGCCAGGAAGGACTTAAAGTTTGTCAGTGACGTTGAGAAGGAAATGGAAACCCTCGTGGAGGCCGTGAATAAGGGAAAGAATAGTAAGAAAAGCCACAGCTTCCCTCCCATGAACAGAGACCACCGCCGGATCATCCATGACTTGGCCCAAGTTTATGGCCTGGAGAGCGTGAGCTATGACAGTGAACCGAAGCGCAATGTGGTGGTCACTGCCATCAGGGGGAAGTCCGTTTGTCCTCCTACCACGCTGACAGGTGTGCTTGAAAGGGAAATGCAGGCACGGCCTCCACCACCGATTCCTCATCACAGACATCAGTCAGACAAGAATCCTGGGAGCAGTAATTTACAGAAAATAACCAAGGAGCCAATAATTGACTATTTTGACGTCCAGGACTAA

翻译后氨基酸参数序列： 点击查看序列

ATGGCGGAGGCGCCTCCTGTCTCAGGTACTTTTAAATTCAATACAGATGCTGCTGAATTCATTCCTCAGGAGAAAAAAAATTCTGGTCTAAATTGTGGGACTCAAAGGAGACTAGACTCTAATAGGATTGGTAGAAGAAATTACAGTTCACCACCTCCCTGTCACCTTTCCAGGCAGGTCCCTTATGATGAAATCTCTGCTGTTCATCAGCATAGTTATCATCCGTCAGGAAGCAAACCTAAGAGTCAGCAGACGTCTTTCCAGTCCTCTCCTTGTAATAAATCGCCCAAGAGCCATGGCCTTCAGAATCAACCTTGGCAGAAATTGAGGAATGAGAAGCACCATATCAGAGTCAAGAAAGCACAGAGTCTTGCTGAGCAGACCTCAGATACAGCTGGATTAGAGAGCTCGACCAGATCAGAGAGTGGGACAGACCTCAGAGAGCATAGTCCTTCTGAGAGTGAGAAGGAAGTTGTGGGTGCAGATCCCAGGGGAGCAAAACCCAAAAAAGCAACACAGTTTGTATACAGCTATGGTAGAGGACCAAAAGTCAAGGGGAAACTCAAATGTGAATGGAGTAACCGAACAACTCCAAAACCGGAGGATGCTGGACCCGAAAGTACCAAACCTGTGGGGGTTTTCCACCCTGACTCTTCAGAGGCATCCTCTAGAAAAGGAGTATTGGATGGGTATGGAGCCAGACGAAATGAGCAGAGAAGATACCCACAGAAAAGGCCTCCCTGGGAAGTGGAGGGGGCCAGGCCACGACCAGGCAGAAATCCACCAAAACAGGAGGGCCACCGACATACAAACGCAGGACACAGAAACAACATGGGCCCCATTCCAAAGGATGACCTCAATGAAAGACCAGCAAAATCTACCTGTGACAGTGAGAACTTGGCAGTCATCAACAAGTCTTCCAGGAGGGTTGACCAAGAGAAATGCACTGTACGGAGGCAGGATCCTCAAGTAGTATCTCCTTTCTCCCGAGGCAAACAGAACCATGTGCTAAAGAATGTGGAAACGCACACAGGTTCTCTAATTGAACAACTAACAACAGAAAAATACGAGTGCATGGTGTGCTGTGAATTGGTTCGTGTCACGGCCCCAGTGTGGAGTTGTCAGAGCTGTTACCATGTGTTTCATTTGAACTGCATAAAGAAATGGGCAAGGTCTCCAGCATCTCAAGCAGATGGCCAGAGTGGTTGGAGGTGCCCTGCCTGTCAGAATGTTTCTGCACATGTTCCTAATACCTACACTTGTTTCTGTGGCAAGGTAAAGAATCCTGAGTGGAGCAGAAATGAAATTCCACATAGCTGTGGTGAGGTTTGTAGAAAGAAACAGCCTGGCCAGGACTGCCCACATTCCTGTAACCTTCTCTGCCATCCAGGACCCTGCCCACCCTGCCCTGCCTTTATGACAAAAACATGTGAATGTGGACGAACCAGGCACACAGTTCGCTGTGGTCAGGCTGTCTCAGTCCACTGTTCTAACCCATGTGAGAATATTTTGAACTGTGGTCAGCACCAGTGTGCTGAGCTGTGCCATGGGGGTCAGTGCCAGCCTTGCCAGATCATTTTGAACCAGGTATGCTATTGCGGCAGCACCTCCCGAGATGTGTTATGTGGAACCGATGTAGGAAAGTCTGATGGATTTGGGGATTTCAGCTGTTTAAAGATATGTGGCAAGGACTTGAAATGCGGTAACCATACATGTTCGCAAGTGTGCCACCCTCAGCCCTGCCAGCAATGCCCACGGCTCCCCCAGCTGGTGCGCTGTTGCCCCTGTGGCCAAACTCCTCTCAGCCAATTGCTAGAACTTGGAAGTAGTAGTCGGAAAACATGCATGGACCCTGTGCCTTCATGTGGAAAAGTGTGCGGCAAGCCTCTGCCTTGTGGTTCCTTAGATTTCATTCATACCTGTGAAAAGCTCTGCCATGAAGGAGACTGTGGACCATGCTCTCGCACATCAGTTATTTCCTGCAGATGCTCTTTCAGAACAAAGGAGCTTCCATGTACCAGTCTCAAAAGTGAAGATGCTACATTTATGTGTGACAAGCGGTGTAACAAGAAACGGTTGTGTGGACGGCATAAATGTAATGAGATATGCTGTGTGGATAAGGAGCACAAGTGTCCTTTGATTTGTGGGAGGAAACTCCGTTGTGGCCTTCATAGGTGTGAAGAACCTTGTCATCGTGGAAACTGCCAGACATGCTGGCAAGCCAGTTTTGATGAATTAACCTGCCATTGTGGTGCATCAGTGATTTACCCTCCAGTTCCCTGTGGTACTAGGCCCCCTGAATGTACCCAAACCTGCGCTAGAGTCCATGAGTGTGACCATCCAGTATATCATTCTTGTCATAGTGAGGAGAAGTGTCCCCCTTGCACTTTCCTAACTCAGAAGTGGTGCATGGGCAAGCATGAGTTTCGGAGCAACATCCCCTGTCACCTGGTTGATATCTCTTGCGGATTACCCTGCAGTGCCACGCTACCATGTGGGATGCACAAATGTCAGAGACTCTGTCACAAAGGGGAGTGTCTTGTGGATGAGCCCTGCAAGCAGCCCTGCACCACCCCCAGAGCTGACTGTGGTCACCCGTGTATGGCACCCTGCCATACCAGCTCACCCTGCCCTGTGACTGCTTGTAAAGCTAAGGTAGAGCTACAGTGTGAATGTGGACGAAGAAAAGAGATGGTGATTTGCTCTGAAGCATCTAGTACTTATCAAAGAATAGCTGCAATCTCCATGGCCTCTAAGATAACAGACATGCAGCTTGGAGGTTCAGTGGAGATCAGCAAGTTAATTACCAAAAAGGAAGTTCATCAAGCCAGGCTGGAGTGTGATGAGGAGTGTTCAGCCTTGGAAAGGAAAAAGAGATTAGCAGAGGCATTTCATATCAGTGAGGATTCTGATCCTTTCAATATACGTTCTTCAGGGTCAAAATTCAGTGATAGTTTGAAAGAAGATGCCAGGAAGGACTTAAAGTTTGTCAGTGACGTTGAGAAGGAAATGGAAACCCTCGTGGAGGCCGTGAATAAGGGAAAGAATAGTAAGAAAAGCCACAGCTTCCCTCCCATGAACAGAGACCACCGCCGGATCATCCATGACTTGGCCCAAGTTTATGGCCTGGAGAGCGTGAGCTATGACAGTGAACCGAAGCGCAATGTGGTGGTCACTGCCATCAGGGGGAAGTCCGTTTGTCCTCCTACCACGCTGACAGGTGTGCTTGAAAGGGAAATGCAGGCACGGCCTCCACCACCGATTCCTCATCACAGACATCAGTCAGACAAGAATCCTGGGAGCAGTAATTTACAGAAAATAACCAAGGAGCCAATAATTGACTATTTTGACGTCCAGGACTAA